It was an even further blow for the Reds as it was Wigan’s second league win in 14 games and first ever at Anfield.
The Lactics seemed a bit wary at first, but Victor Moses broke through to try his luck, but defender Martin Skrtel was able to block the early shot.
Unfortunately for Moses, he would see Skrtel’s boot when the Slovakian gave a high kick to the face in an effort to block him again. Moses had to leave the field after some treatment, but it earned Wigan a penalty at the half hour mark, which Shaun Maloney took and put past Pepe Reina for his first goal in a Wigan shirt.
Lactic keeper Ali Al Habsi became busy after that. Liverpool responded passionately but the keeper kept denying them a goal, including a curl by Luis Suarez and a shot by Steven Gerrard.
Manager Kenny Dalglish made an early change at halftime, replacing Jordan Henderson with striker Andy Carroll.
Two minutes into the second half, the Reds levelled up when Gerrard neatly passed the ball to Suarez to put it past Al Habsi.
The Uruguayan seemingly scored another goal only a few moments later. Skrtel’s header stumbled near the goal, and Suarez fumbled it into the net, but the goal was disallowed when the referee ruled it bounced off his arm.
Wigan responded with another goal to put them in the lead. James McCarthy’s shot was blocked by Jamie Carragher, but the ball was picked up by Gary Caldwell, and he then put it past a shocked Reina.
Liverpool fought back but in the end were defeated, the fifth time in six league games, and it sees the Reds still in seventh on the Barclay’s Premier League table.
